The clinical endpoint in weight loss was not all that impressive for those who are majorly obese and the pill isn't approved for use in those who are "just trying to lose those last ten pounds". Furthermore, all weight lost is regained once the medication has stopped. I might be happier if the degree of weight loss was 20% which is really what most of these guys need but it was only around 5% which probably isn't going to be enough to have a major effect on all the major disease end points related to obesity. I am also fairly confident that this medication has not been proven to affect those end points either.
Anyhow, it probably does bode well for its competitor's approval as well but I'm not convinced either is going to be the panacea that anyone was hoping for from these medications.
I can see these meds selling reasonably well for a couple of years before seeing a fall off in sales.
The only thing that really helps the majorly obese is diet and exercise for the few who can change their lifestyle or more likely some form of gastric reduction as barbaric as it is.