Always choose lifestyle.
I recently took one-step back in pay to take 2 steps forward in a year. That being said I am now leaps forward in lifestyle. I took a huge pay cut and moved on to a new job that allows for a schedule, stable pay cheque (granted it is less...But there is something to be said about stability after a decade of not knowing how much you will make at the end of the year), benefits, the actual work load is less stressful, safer, and I still enjoy what I do.
Most importantly I spend more time at home and I'm able to enjoy many things I missed out on in the past. To those that say work 6 days a week to be successful ... What an absurd statement. Go to a hospice and start interviewing patients about regrets in life. I'd bet my last dollar that you would not find many that wished they worked 6 day and 60 hour work weeks. I put work first for the first decade of my career. I must be a slow learner because it took 12 years of saying no to friends and family and foolishly saying yes to work to now realize that is an awful life to lead.
I worked 10 days last month and I look forward to only working 8 this month. Work smarter, not harder. I consider myself successful even though I work substantially less than 6 days a week and much less then 60 hour work weeks.